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Targeting the proteasome: a new route to anticancer treatment

โœ Scribed by Katharine Pestell


Book ID
114410280
Publisher
Elsevier Science
Year
2002
Weight
42 KB
Volume
1
Category
Article
ISSN
1477-3627

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## Abstract The ubiquitin-proteasome system is responsible for the degradation of most intracellular proteins, including those that control cell cycle progression, apoptosis, signal transduction and the NF-ฮบB transcriptional pathway. Aberrations in the ubiquitin-proteasome system underlie the patho