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Targeting the PDZ domains of molecular scaffolds of transmembrane ion channels

✍ Scribed by Andrea Piserchio; Mark Spaller; Dale F. Mierke

Book ID
105634566
Publisher
American Association of Pharmaceutical Scientists
Year
2006
Tongue
English
Weight
430 KB
Volume
8
Category
Article
ISSN
1550-7416

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Transmembrane domains of viral ion chann
Transmembrane domains of viral ion channel proteins: A molecular dynamics simulation study
✍ Wolfgang B. Fischer; Lucy R. Forrest; Graham R. Smith; Mark S. P. Sansom πŸ“‚ Article πŸ“… 2000 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 300 KB πŸ‘ 3 views

Nanosecond molecular dynamics simulations in a fully solvated phospholipid bilayer have been performed on single transmembrane ␣-helices from three putative ion channel proteins encoded by viruses: NB (from influenza B), CM2 (from influenza C), and Vpu (from HIV-1). ␣-Helix stability is maintained w