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Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases

✍ Scribed by Thomas A Waldmann


Book ID
120707147
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
50 KB
Volume
6
Category
Article
ISSN
1478-6354

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The interleukin-15/interleukin-15 recept
✍ Silvia Bulfone-Paus; Elena Bulanova; Vadim Budagian; Ralf Paus πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 601 KB

## Abstract Interleukin‐15 (IL‐15) is a pleiotropic cytokine of the 4 α‐helix bundle family, which binds to a receptor complex that displays common elements with the IL‐2 receptor and a unique high‐affinity Ξ± chain. This review focuses on juxtacrine and reverse signaling levels in the IL‐15/IL‐15R