Targeting the growth factors and angiogenesis pathways: Small molecules in solid tumors
✍ Scribed by David Berz; Harold Wanebo
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 316 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Interaction between cancer cells and adjacent stromal cells is important to promote tumor development. Our aim was to study total COX‐2 mRNA expression in both cancer cells and surrounding stromal cells and its association with angiogenic factor VEGF mRNA expression, tumor angiogenesis
## Abstract Ascochlorin, a non‐toxic prenylphenol compound derived from the fungus __Ascochyta viciae__, has been shown recently to have anti‐cancer effects on various human cancer cells. However, the precise molecular mechanism of this anti‐cancer activity remains to be elucidated. Here, we invest
## Abstract During the last decade, a central role for insulin‐like growth factor 1 (IGF‐1) in the pathophysiology of multiple myeloma (MM) has been well established. IGF‐I provided by the tumor–microenvironment interaction may directly and indirectly facilitate the migration, survival and expansio
## BACKGROUND. Antagonists of bombesin/gastrin-releasing peptide (BN/GRP) have been developed to block the autocrine stimulatory effect of BN/GRP on tumors such as small cell lung carcinoma (SCLC). Although several studies have addressed the intracellular events that follow the formation of the re
## Abstract Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas‐mediated tumor killing, During tumor progression FasL‐expressing tumor cells are involved in __counterattacking__ to kill tumor‐infiltr