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Targeting the function of the HER2 oncogene in human cancer therapeutics

โœ Scribed by Moasser, M M


Book ID
110072474
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
246 KB
Volume
26
Category
Article
ISSN
0950-9232

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Expression of the p185 encoded by her2 o
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The human homolog of the rat neu oncogene, HER2 (also termed c-erf~B2) has been demonstrated in amplified form in human breast tumors with poor prognosis. Although amplification of the gene correlates with expression of a 185-kDa transmembrane glycoprotein, no extensive information is available rega