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Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma

✍ Scribed by Michael Höpfner; Andreas P. Sutter; Alexander Huether; Detlef Schuppan; Martin Zeitz; Hans Scherübl

Book ID
116650487
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
361 KB
Volume
41
Category
Article
ISSN
0168-8278

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## Abstract Esophageal cancer is the sixth most common cause of cancer‐related death worldwide. Because of very poor 5‐year survival new therapeutic approaches are mandatory. Erlotinib (Tarceva™), an inhibitor of epidermal growth factor receptor tyrosine kinase (EGFR‐TK), potently suppresses the gr