Targeting TGF–β for treatment of disease
✍ Scribed by Border, Wayne A.; Noble, Nancy A.
- Book ID
- 109931602
- Publisher
- Nature Publishing Group
- Year
- 1995
- Tongue
- English
- Weight
- 784 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1078-8956
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## BACKGROUND Tumor endothelium represents a valuable target for cancer therapy. The vasculature plays a critical role in the survival and continued growth of solid tumor masses; in addition, the inherent differences between tumor blood vessels and blood vessels associated with normal
## Abstract Finding inhibitors of the first step of the amyloid cascade, Aβ~42~ generation, is a major goal of Alzheimer's disease drug development. Two target protease activities, β‐and γ‐secretase, were detected more than 10 years ago but progress in this area has been slow because the enzymes we