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Targeting Ras and Rho GTPases as opportunities for cancer therapeutics

โœ Scribed by Katharine Walker; Michael F Olson

Book ID
116504942
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
346 KB
Volume
15
Category
Article
ISSN
0959-437X

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โœ Marc Symons ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 579 KB

The small GTP-binding proteins Rac and Rho are key control elements in the reorganization of the actin cytoskeleton induced by growth factors or oncogenic Ras. It has been established recently that Rac and Rho also play a crucial role in Ras transformation. This suggests that the elements in the pat