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Targeting PI3K/AKT Pathway is an Effective Strategy for the Treatment of Neuroendocrine Tumors Harboring PIK3CA Mutations

✍ Scribed by Jun Song; Jing Li; Ji Tae Kim; Heidi Weiss; Courtney M. Townsend; B.M. Evers


Book ID
119432319
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
122 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Fibroblast growth factor‐1 (FGF1), a prototypic member of the FGF family, is a potent angiogenic factor. Although FGF‐stimulated angiogenesis has been extensively studied, the molecular mechanisms regulating FGF1‐induced angiogenesis are poorly understood in vivo. Fumagillin, an antiang