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Targeting p53 by small molecules in hematological malignancies

✍ Scribed by Manujendra N Saha, Lugui Qiu, Hong Chang


Book ID
120698269
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
264 KB
Volume
6
Category
Article
ISSN
1756-8722

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A computerized database is described that contains information about 507 mutations in the p53 gene of hematologic tumors and corresponding cell lines. Analysis of these mutations indicated the following findings: First, mutational spectrum analysis in these tumors was found to be similar to the patt