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Targeting of tumor angiogenesis using engineered Trojan Horse mesenchymal stem cells

✍ Scribed by Claudius Conrad; Yves Hüsemann; Hanno Niess; Irene von Lüttichau; Ralf Huss; Christian Bauer; Karl-Walter Jauch; Christoph Klein; Christiane Bruns; Peter Nelson

Book ID
113679403
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
107 KB
Volume
209
Category
Article
ISSN
1072-7515

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## Abstract ## Background Inhibition of tumor‐induced angiogenesis may restrict tumor growth and metastasis. Long‐term systemic delivery of angiogenic inhibitors is associated with toxicity, as well as other severe side‐effects. The utility of cells as vehicles for gene therapy to deliver therapeu