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Targeting of a CCK2receptor splice variant with111In-labelled cholecystokinin-8 (CCK8) and111In-labelled minigastrin

✍ Scribed by Peter Laverman; Susan Roosenburg; Martin Gotthardt; Jeseong Park; Wim J. G. Oyen; Marion de Jong; Mark R. Hellmich; Floris P. J. T. Rutjes; Floris L. van Delft; Otto C. Boerman

Publisher
Springer
Year
2007
Tongue
English
Weight
233 KB
Volume
35
Category
Article
ISSN
0340-6997

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The [Tc(N)(PNP)]2+ metal fragment labele
The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitro and in vivo studies
✍ Stefania Agostini; Cristina Bolzati; Eliana DidonΓ¨; Mario Cavazza-Ceccato; Fiore πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 169 KB

## Abstract The radiolabeling of the natural octapeptide CCK8, derivatized with a cysteine residue (Cys‐Gly‐CCK8), by using the metal fragment [^99m^Tc(N)(PNP3)]^2+^ (PNP3 = __N__,__N__‐bis(dimethoxypropylphosphinoethyl)methoxyethylamine) is reported. The [^99m^Tc(N)(NS‐Cys‐Gly‐CCK8)(PNP3)]^+^ comp