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Targeting microRNAs in cancer: rationale, strategies and challenges

✍ Scribed by Garzon, Ramiro; Marcucci, Guido; Croce, Carlo M.


Book ID
109951112
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
505 KB
Volume
9
Category
Article
ISSN
1474-1776

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## Abstract MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate protein‐coding genes. To identify miRNAs that have a tumor suppressive function in bladder cancer (BC), 156 miRNAs were screened in 14 BCs, 5 normal bladder epithelium (NBE) samples and 3 BC cell lines. We identified a