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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

โœ Scribed by David B Agus; Robert W Akita; William D Fox; Gail D Lewis; Brian Higgins; Paul I Pisacane; Julie A Lofgren; Charles Tindell; Douglas P Evans; Krista Maiese; Howard I Scher; Mark X Sliwkowski


Book ID
114413206
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
450 KB
Volume
2
Category
Article
ISSN
1535-6108

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โœ Thirupandiyur S. Udayakumar; Elisabeth L. Bair; Raymond B. Nagle; G. Timothy Bow ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 261 KB

## Abstract Previously we have shown that the matrix metalloproteinase matrilysin (MMPโ€7) is overexpressed in human prostate cancers compared with normal epithelium. However, the mechanism for this overexpression is not understood. Human prostate fibroblasts have been shown to express certain fibro