✦ LIBER ✦

Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells

✍ Scribed by Lebedeva, I V; Su, Z-Z; Emdad, L; Kolomeyer, A; Sarkar, D; Kitada, S; Waxman, S; Reed, J C; Fisher, P B

Book ID: 110070825
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 483 KB
Volume: 26
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1209813

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Induction of reactive oxygen species ren

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis

✍ Lebedeva, Irina V; Su, Zao-zhong; Sarkar, Devanand; Gopalkrishnan, Rahul V; Waxm 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 485 KB

MicroRNAs targeting mutant K-ras by elec

MicroRNAs targeting mutant K-ras by electrotransfer inhibit human colorectal adenocarcinoma cell growth in vitro and in vivo

✍ Vidic, S; Markelc, B; Sersa, G; Coer, A; Kamensek, U; Tevz, G; Kranjc, S; Cemaza 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 636 KB

The cannabinoid δ9-tetrahydrocannabinol

The cannabinoid δ9-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

✍ Alexander Greenhough; Helena A. Patsos; Ann C. Williams; Christos Paraskeva 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 310 KB

## Abstract Deregulation of cell survival pathways and resistance to apoptosis are widely accepted to be fundamental aspects of tumorigenesis. As in many tumours, the aberrant growth and survival of colorectal tumour cells is dependent upon a small number of highly activated signalling pathways, th