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Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

✍ Scribed by Bjarnadottir, Olöf (author);Romero, Quinci (author);Bendahl, Pär Ola (author);Jirström, Karin (author);Rydén, Lisa (author);Loman, Niklas (author);Uhlén, Mathias (author);Johannesson, Henrik (author);Rose, Carsten (author);Grabau, Dorthe (author);Borgquist, Signe (author)

Book ID
120050531
Publisher
Springer US
Year
2013
Tongue
English
Weight
413 KB
Volume
138
Category
Article
ISSN
0167-6806

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✍ Signe Borgquist; Soraya Djerbi; Fredrik Pontén; Lola Anagnostaki; Malin Goldman; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 287 KB

## Abstract Although several studies have reported on the anti‐tumoural properties exerted by 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMG‐CoAR) inhibitors (statins), the __in vivo__ expression of HMG‐CoAR in human cancer has been considerably less investigated. In our study, we examined th