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Targeting gene therapy vectors to the vascular endothelium

✍ Scribed by Lorraine M. Work; Stuart A. Nicklin; Andrew H. Baker

Book ID: 107533722
Publisher: Current Science Inc.
Year: 2003
Tongue: English
Weight: 654 KB
Volume: 5
Category: Article
ISSN: 1523-3804
DOI: 10.1007/s11883-003-0019-9

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## Abstract ## Background One of the drawbacks of the currently available vectors for gene therapy is the lack of selectivity in gene delivery. We have therefore investigated a strategy to generate immunoliposomes to target non‐viral vectors to cell surface receptors on endothelium. ## Materials