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Targeting DNA methylation for epigenetic therapy

✍ Scribed by Xiaojing Yang; Fides Lay; Han Han; Peter A. Jones

Book ID
116918982
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
465 KB
Volume
31
Category
Article
ISSN
0165-6147

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## Abstract During differentiation and development cells undergo dramatic morphological and functional changes without any change in the DNA sequence. The underlying changes of gene expression patterns are established and maintained by epigenetic processes. Early mechanistic insights came from the