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Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody

✍ Scribed by Petra Kocbek; Nataša Obermajer; Mateja Cegnar; Janko Kos; Julijana Kristl

Book ID
113691528
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
844 KB
Volume
120
Category
Article
ISSN
0168-3659

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## Abstract Two kinds of immunoconjugate (T‐3M and T‐11M) of murine monoclonal antibody with mitomycin C (MMC) were developed using spacers containing a disulfide (T‐3M) or thiocarbamate (T‐11M) bond. A murine monoclonal antibody (NCC‐LU‐243) raised against a human small cell lung carcinoma cell li