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Targeting cAMP in chronic lymphocytic leukemia: a pathway-dependent approach for the treatment of leukemia and lymphoma

✍ Scribed by Murray, Fiona; Insel, Paul A


Book ID
120316515
Publisher
Informa plc
Year
2013
Tongue
English
Weight
725 KB
Volume
17
Category
Article
ISSN
1472-8222

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Cell division and apoptosis (programmed cell death) are the two major physiological processes which control the size of cell populations. Chronic lymphocytic leukaemia arises as a result of the clonal expansion of, usually B-, lymphocytes in which a dysregulation of apoptosis leads to prolonged cell