c-Met represents a potential therapeutic
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Hanning You; Wei Ding; Hien Dang; Yixing Jiang; C. Bart Rountree
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Article
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2011
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John Wiley and Sons
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English
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c-Met, a high-affinity receptor for hepatocyte growth factor (HGF), plays a critical role in cancer growth, invasion, and metastasis. Hepatocellular carcinoma (HCC) patients with an active HGF/c-Met signaling pathway have a significantly worse prognosis. Although targeting the HGF/c-Met pathway has