Self-Eating on Demand: Autophagy in Canc
β Edited by: Patrizia Agostinis and Jon D. Lane
π Library
π Russian
β¦ LIBER β¦
π
Targeting Autophagy in Cancer Therapy
β Scribed by Jin-Ming Yang (eds.)
- Publisher
- Springer International Publishing
- Year
- 2016
- Tongue
- English
- Leaves
- 146
- Series
- Current Cancer Research
- Edition
- 1
- Category
- Library
β¬ Acquire This Volume
No coin nor oath required. For personal study only.
β¦ Synopsis
This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting autophagy in cancer stem cells, and roles of autophagy in cancer immunotherapy. In addition, the volume will review applications of system biology and bioinformatics approaches to discovering cancer therapeutic targets in the autophagy regulatory network.
The volume will be beneficial for a variety of basic and clinical scientists, including cancer biologists, autophagy researchers, pharmacologists, and clinical oncologists who wish to delve more deeply into this field of cancer research.
This volume will be the first book to focus solely on autophagy as a target in cancer therapy. As well, it will comprehensively discuss the roles of autophagy in most currently available cancer treatments.
β¦ Table of Contents
Front Matter....Pages i-vii
Autophagy as a Therapeutic Target in Cancer....Pages 1-16
Autophagy in Cancer Cells vs. Cancer Tissues: Two Different Stories....Pages 17-38
Small-Molecule Regulators of Autophagy as Potential Anti-cancer Therapy....Pages 39-57
Regulation of Autophagy by microRNAs: Implications in Cancer Therapy....Pages 59-84
Targeting PI3-Kinases in Modulating Autophagy and Anti-cancer Therapy....Pages 85-97
Adult and Cancer Stem Cells: Perspectives on Autophagic Fate Determinations and Molecular Intervention....Pages 99-116
Role of Autophagy in Tumor Progression and Regression....Pages 117-131
Erratum to: Adult and Cancer Stem Cells: Perspectives on Autophagic Fate Determinations and Molecular Intervention....Pages E1-E1
Back Matter....Pages 133-141
β¦ Subjects
Cancer Research
π SIMILAR VOLUMES
Targeted Therapies in Cancer
β Hans H. Kreipe MD, Reinhard von Wasielewski MD (auth.), Prof. Dr. med. Manfred D
π Library
π
2007
π Springer-Verlag Berlin Heidelberg
π English
<p><P>From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the bodyβs non-neoplastic cells. The resultant problems with unwanted side effects are compoun
Advances in Targeted Cancer Therapy
β Richard M. Schultz
π Library
π
2005
π BirkhΓ€user Basel
π German
<P>This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and ant
Advances in Targeted Cancer Therapy
β Richard M. Schultz (auth.), Prof. Dr. Paul L. Herrling, Alex Matter M.D., Dr. Ri
π Library
π
2005
π BirkhΓ€user Basel
π English
<p><P>There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully th
Tumor Targeting in Cancer Therapy
β Tarunendu Ghose (auth.), Michel PagΓ© PhD (eds.)
π Library
π
2002
π Humana Press
π English
<p>After many years of vigorous effort, the use of antibodies to target tumors has become highly successful both clinically and commercially. In Tumor Targeting in Cancer Therapy, Dr. Michel PagΓ© and a panel of authoritative experts from the drug industry, clinics, and academia introduce the princip
Targeted Therapies in Breast Cancer
β Harold Burstein
π Library
π
2011
π Oxford University Press
π English
The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of brea