Recombinant single-chain antibody fusion
✍
Yuying Liu; Lawrence H. Cheung; John W. Marks; Michael G. Rosenblum
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
French
⚖ 673 KB
## Abstract Fusion constructs targeting tumor cells have significant potential applications against both solid tumors and hematologic malignancies. We developed a fusion construct of tumor necrosis factor (TNF) and a single‐chain antibody (scFvMEL) recognizing the gp240 antigen on human melanoma ce