Biochemical mechanisms in colon xenograf
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Peter J. Houghton; Janet A. Houghton; Bonni J. Hazelton; Saeed Radparvar
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Article
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1989
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Springer US
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English
β 764 KB
Growth of human adenocarcinomas of the colon and rectum in immunoincompetent mice has allowed for a greater understanding of the interaction of 5-fluorouracil, its metabolism, and mechanism(s) of cytotoxicity under conditions of tumor growth in situ. Conversely, this agent has proven to be a useful