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Targeted silencing of heparanase gene by small interfering RNA inhibits invasiveness and metastasis of osteosarcoma cells

โœ Scribed by Lei Fan; Qiang Wu; Xiaojuan Xing; Yudong Liu; Zengwu Shao


Book ID
107408188
Publisher
Springer-Verlag
Year
2011
Tongue
Chinese
Weight
459 KB
Volume
31
Category
Article
ISSN
0510-9752

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## Abstract In order to develop a gene therapy to human cytomegalovirus (HCMV), RNA interference (RNAi) was employed to inhibit the expression of HCMV UL122 gene __in vitro__. Recombinant vector pUL122โ€EGFP, which expressed UL122โ€EGFP fusion protein, and recombinant vectors psi122โ€1, psi122โ€2 and p