## Abstract The biosynthesis of the zinc finger transcription factor Egrβ1 is stimulated by many extracellular signaling molecules including hormones, neurotransmitters, growth and differentiation factors, and cytotoxic metabolites. The 5β²βflanking region of the __Egrβ1__ gene contains genetic elem
β¦ LIBER β¦
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors
β Scribed by Jouvenot, Y; Ginjala, V; Zhang, L; Liu, P-Q; Oshimura, M; Feinberg, A P; Wolffe, A P; Ohlsson, Rolf; Gregory, P D
- Book ID
- 110039232
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 343 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0969-7128
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## Abstract The transcription factors Sp1, Sp3, and Egrβ1 bind with their zinc finger DNAβbinding domains to GCβrich sequences in the regulatory regions of their target genes. The similarity of the DNAβbinding sites of Sp1, Sp3, and Egrβ1 has triggered the hypothesis that they compete for the same