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Targeted radionuclide therapy in head and neck cancer

✍ Scribed by Marika V. Nestor

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
262 KB
Volume
32
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

There is great potential for targeted radionuclide therapy (TRT) in the treatment of head and neck cancer. In recent years, developments in fields such as antigen screening, protein engineering, and cancer biology have facilitated the rational design of targeted pharmaceuticals, with monoclonal antibodies forming the most rapidly expanding category. TRT may be a promising way to improve targeted treatment, especially in head and neck cancer, because of the intrinsic radiosensitivity of this tumor type. TRT may also provide a good foundation on which to build rational biologic combination therapies. In the next few years the use of TRT may offer new opportunities for further improvement of the therapeutic ratio that potentially may obviate or reduce the need for conventional cytotoxics. Β© 2009 Wiley Periodicals, Inc. Head Neck, 2010

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