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Targeted Quantum Dot Conjugates for siRNA Delivery

โœ Scribed by Derfus, Austin M.; Chen, Alice A.; Min, Dal-Hee; Ruoslahti, Erkki; Bhatia, Sangeeta N.

Book ID
118068831
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
348 KB
Volume
18
Category
Article
ISSN
1043-1802

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Hyaluronic acidโ€“polyethyleneimine conjug
Hyaluronic acidโ€“polyethyleneimine conjugate for target specific intracellular delivery of siRNA
โœ Ge Jiang; Kitae Park; Jiseok Kim; Ki Su Kim; Eun Ju Oh; Hyungu Kang; Su-Eun Han; ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 286 KB

## Abstract A novel target specific small interfering RNA (siRNA) delivery system was successfully developed using polyethyleneimine (PEI)โ€“hyaluronic acid (HA) conjugate. Antiโ€PGL3โ€Luc siRNA was used as a model system suppressing the PGL3โ€Luc gene expression. The siRNA/PEIโ€HA complex with an averag