✦ LIBER ✦

Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer

✍ Scribed by Muthu K. Shanmugam; An H. Nguyen; Alan P. Kumar; Benny K.H. Tan; Gautam Sethi

Book ID: 116335883
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 569 KB
Volume: 320
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2012.02.037

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The role of the tumor-microenvironment i

The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets

✍ Wood, Steven L.; Pernemalm, Maria; Crosbie, Philip A.; Whetton, Anthony D. 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 926 KB

549 POSTER The RANKL inhibitor osteoprot

549 POSTER The RANKL inhibitor osteoprotegerin (OPG) inhibits tumor growth, prevents tumor-induced osteolysis, and significantly improves survival in a mouse model of breast cancer bone metastasis

✍ J. Canon; M. Roudier; R. Bryant; R. Radinsky; W. Dougall 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 71 KB

450 Glucocorticoids frequently induce su

450 Glucocorticoids frequently induce survival and growth in tumor cells by activation of classical survival and proliferation pathways which should be avoided during anti-cancer therapy

✍ I. Jeremias; S. Gündisch; E. Baader; E. Amtmann; H. Ehrhardt 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 44 KB

Inhibition of cell proliferation, invasi

Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model

✍ Bal L. Lokeshwar; Marie G. Selzer; Bao-Qian Zhu; Norman L. Block; Lorne M. Golub 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 460 KB

## Abstract Antibiotic forms of tetracycline exhibit antitumor activity in some tumor models. However, their low __in vivo__ efficacy and associated morbidity limit their long‐term application in cancer therapy. This report appraises the efficacy of doxycycline (DC) and non‐antimicrobial, chemicall

Gene therapy with RNAi targeting UHRF1 d

Gene therapy with RNAi targeting UHRF1 driven by tumor-specific promoter inhibits tumor growth and enhances the sensitivity of chemotherapeutic drug in breast cancer in vitro and in vivo

✍ Lin Fang; Li Shanqu; Gao Ping; He Ting; Wang Xi; Dong Ke; Long Min; Wei Junxia; 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 694 KB

The role of Fas ligand and transforming

The role of Fas ligand and transforming growth factor β in tumor progression : Molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy

✍ Ryungsa Kim; Manabu Emi; Kazuaki Tanabe; Yoko Uchida; Tetsuya Toge 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB

## Abstract Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas‐mediated tumor killing, During tumor progression FasL‐expressing tumor cells are involved in __counterattacking__ to kill tumor‐infiltr