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Targeted gene transfer by adenoviral and retroviral vectors in hepatocellular carcinoma cells


Book ID
118566513
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
63 KB
Volume
21
Category
Article
ISSN
0168-8278

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## Abstract ## Background Because gene therapy of the future will primarily take an __in vivo__ approach, a number of problems associated with its current implementation exist. Currently, repeated delivery of a vector __in vivo__ is necessary to ensure adequate transfer of the therapeutic gene. Th

Gene delivery using a receptor-mediated
✍ Terence Kin-Wah Lee; Jun-Song Han; Sheung-Tat Fan; Zheng-Dong Liang; Pei-Kun Tia πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 650 KB

For gene therapy to be effective in cancers, it is necessary to deliver therapeutic genes into cells with high specificity and efficiency. In this study, we examined the in vitro and in vivo gene delivery efficiency of a new, growth receptor-mediated gene transfer system in hepatocellular carcinoma