Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice

Targeted disruption of the heat shock tr

Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis

✍ Guanghu Wang; Jing Zhang; Demetrius Moskophidis; Nahid F. Mivechi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 560 KB

## Abstract Summary: Heat shock transcription factors (Hsfs) are major transactivators of heat shock protein (Hsp) genes in the response to stress stimuli, but are also thought to be involved in embryonic development and spermatogenesis. Among the three known mammalian Hsfs, Hsf1 is recognized as t