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Targeted disruption of PPARγ in bone marrow stromal cells reveals its role in aging-induced bone loss

✍ Scribed by Xing-Ming Shi; Guomin Ou; Mark Hamrick; Kehong Ding; Shang-You Yang; Frank Gonzalez; Barbara Kream; Carlos Isales

Book ID: 116320922
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 52 KB
Volume: 43
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2008.08.009

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## Abstract Bone marrow stromal cells (MSC), which represent a population of multipotential mesenchymal stem cells, have been reported to undergo rapid and robust transformation into neuron‐like phenotypes in vitro following treatment with chemical induction medium including dimethyl sulfoxide (DMS