## Abstract Glial cell line‐derived neurotrophic factor (GDNF) enhances the survival of a variety of neurons, including photoreceptors (PR) in the retina. In contrast to most other GDNF receptive neurons, GDNF does, however, not exert its neuroprotective activity directly on PR neurons but transmit
Targeted disruption of Müller cell metabolism induces photoreceptor dysmorphogenesis
✍ Scribed by Monica M. Jablonski; Alessandro Iannaccone
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 769 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0894-1491
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Neuronal degeneration and aberrant neovascularization are common problems of ischemic retinopathies. Pigment epithelium‐derived factor (PEDF), a neuroprotective protein and an inhibitor of angiogenesis, is produced by retinal glial (Müller) cells and can counterbalance elevated levels o
During vertebrate neural retina development, the relationship between mitotic activity in progenitor cells and the acquisition of a mature cell phenotype remains an area of controversy. The Müller glial cell has long been recognized as one of the last cell types of the retina to mature, which occurs
## Abstract We have investigated the expression and cellular localization of clusterin in the rat retina following ischemia induced by transiently increasing the intraocular pressure. In the normal retina, weak clusterin immunoreactivity was visible in Müller cell profiles located in the inner nucl
## Abstract High blood ammonia, elevated glutamine, and hyponatremia are pathogenic factors contributing to astrocytic swelling and brain edema in liver failure. We investigated the effects of hypoosmolarity, ammonia, and glutamine on the induction of glial cell swelling in freshly isolated slices
A previous study demonstrated the release of newly loaded radiolabelled taurine (Tau) from cultured rabbit Miiller glia not only following typical cell volumeincreasing treatments with high (65 mM) potassium ions or hypotonic media, but also with ammonium chloride (further referred to as ammonia), i