𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Targeted Dendrimeric Anticancer Prodrug: A Methotrexate-Folic Acid-Poly(amidoamine) Conjugate and a Novel, Rapid, “One Pot” Synthetic Approach

✍ Scribed by Zhang, Yuehua; Thomas, Thommey P.; Desai, Ankur; Zong, Hong; Leroueil, Pascale R.; Majoros, Istvan J.; Baker, James R.

Book ID
127051556
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
724 KB
Volume
21
Category
Article
ISSN
1043-1802

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Targeted Dendrimeric Anticancer Prodrug:
Targeted Dendrimeric Anticancer Prodrug: A Methotrexate-Folic Acid-Poly(amidoamine) Conjugate and a Novel, Rapid, “One Pot” Synthetic Approach
✍ Zhang, Yuehua; Thomas, Thommey P.; Desai, Ankur; Zong, Hong; Leroueil, Pascale R 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 724 KB

A targeted dendrimeric anticancer prodrug, a conjugate of generation 5 (G5) polyamidoamine (PAMAM) dendrimer, folic acid (FA), and methotrexate (MTX), has been successfully synthesized by using a novel "one pot" approach which is simple, reproducible, and feasible for large-scale synthesis. All dend