✦ LIBER ✦

Targeted agents: How to select the winners in preclinical and early clinical studies?

✍ Scribed by Rachel Goodwin; Giuseppe Giaccone; Hilary Calvert; Marinus Lobbezoo; Elizabeth A. Eisenhauer

Book ID: 116430892
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 218 KB
Volume: 48
Category: Article
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2011.09.024

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The successes and limitations of preclin

The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell-surface-targeted biological agents in patients

✍ Andrew G Polson; Reina N Fuji 📂 Article 📅 2012 🏛 Nature Publishing Group 🌐 English ⚖ 155 KB

The use of vascular biomarkers and imagi

The use of vascular biomarkers and imaging studies in the early clinical development of anti-tumour agents targeting angiogenesis

✍ J. DREVS; V. SCHNEIDER 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 937 KB

Novel Targeted Agents and the Need to Re

Novel Targeted Agents and the Need to Refine Clinical End Points in Chronic Lymphocytic Leukemia

✍ Cheson, B. D.; Byrd, J. C.; Rai, K. R.; Kay, N. E.; O'Brien, S. M.; Flinn, I. W. 📂 Article 📅 2012 🏛 American Society of Clinical Oncology 🌐 English ⚖ 66 KB

Evaluation of selection procedures in re

Evaluation of selection procedures in relation to performances in the undergraduate medical course: Part 2: Additional time taken to complete preclinical and clinical courses of study

✍ P. S. S. S. RAO 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB

The effectiveness of multi-target agents

The effectiveness of multi-target agents in schizophrenia and mood disorders: Relevance of receptor signature to clinical action

✍ Erik H.F. Wong; Frank I. Tarazi; Mohammed Shahid 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 476 KB

Preclinical and clinical studies of estr

Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer

✍ Marion T Weigel, Zara Ghazoui, Anita Dunbier, Sunil Pancholi, Mitch Dowsett, Les 📂 Article 📅 2012 🏛 BioMed Central 🌐 English ⚖ 710 KB