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Target-Specific Ligands and Gadolinium-Based Complexes for Imaging of Dopamine Receptors: Synthesis, Binding Affinity, and Relaxivity

✍ Scribed by Zigelboim, Isaac; Weissberg, Avi; Cohen, Yoram


Book ID
120563834
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
603 KB
Volume
78
Category
Article
ISSN
0022-3263

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The three novel pyridine-containing 12-membered macrocyclic ligands 1 Β± 3 were synthesized. The coordinating arms are represented by three acetate moieties in 1 and 3 and by one acetate and two phosphonate moieties in 2. In all three ligands, the acetate arm in the distal position is substituted, wi