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Target Search of N Sliding Proteins on a DNA

✍ Scribed by Sokolov, Igor M.; Metzler, Ralf; Pant, Kiran; Williams, Mark C.


Book ID
119919304
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
155 KB
Volume
89
Category
Article
ISSN
0006-3495

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Genomic expression depends critically on both the ability of regulatory proteins to locate specific target sites on DNA within seconds and on the formation of long-lived (many minutes) complexes between these proteins and the DNA. Equilibrium experiments show that indeed regulatory proteins bind tig