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Target cell heterogeneity in murine leukemia virus infection: III. Identification of susceptible Lyt 1+ and resistant Lyt 2+ T-cell subsets following in vitro infection with Friend murine leukemia virus

โœ Scribed by Dale D. Isaak; Robert M. Miceli; Jeffrey P. Lake


Book ID
113132935
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
836 KB
Volume
88
Category
Article
ISSN
0008-8749

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## Abstract The permissiveness of normal splenic lymphocytes to Friend murine leukemia virus was determined by enumeration of cells producing infectious MuLV following infection with Friend virus __in vitro.__ The infection was enhanced greatly in the presence of mitogens in the culture medium. The

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## Abstract The infection of isolated B and T cells by a murine leukemia virus (Friend) (MuLVโ€F) was studied both __in vitro__ and __in vitro__ with an implanted diffusion chamber system. Lymphocytes were obtained from pools of normal spleen cells by filtration of the cell suspension through a nylo