CYP2D6 genotyping strategy based on gene
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Elke Schaeffeler; Matthias Schwab; Michel Eichelbaum; Ulrich M. Zanger
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Article
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2003
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John Wiley and Sons
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English
β 338 KB
The genetic polymorphism of the cytochrome P450 monooxygenase, CYP2D6, comprises at least 43 alleles giving rise to distinct drug metabolism phenotypes termed ultrarapid, extensive, intermediate, and poor metabolizers. As a consequence, drug side effects or lack of drug effect may occur if standard