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Tankyrase, a positive regulator of telomere elongation, is over expressed in human breast cancer

✍ Scribed by Stefania Gelmini; Melissa Poggesi; Vito Distante; Simonetta Bianchi; Lisa Simi; Michaela Luconi; Claudia Casini Raggi; Luigi Cataliotti; Mario Pazzagli; Claudio Orlando


Book ID
116333187
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
119 KB
Volume
216
Category
Article
ISSN
0304-3835

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Estrogen regulated expression of the p21
✍ Soma Mandal; James R. Davie πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 183 KB

## Abstract The cyclin‐dependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30–60 min independent of new protein synthesis in the estrogen recept