Tandem synthesis of 2,3-dihydroquinazolin-4(1H)-ones on grinding under solvent-free conditions
✍ Scribed by Quan-Sheng Ding; Ji-Lei Zhang; Jiu-Xi Chen; Miao-Chang Liu; Jin-Chang Ding; Hua-Yue Wu
- Book ID
- 111647003
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 184 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.759
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## Abstract A simple, efficient and convenient one‐pot synthesis of 2,3‐dihydroquinazolin‐4(1__H__)‐one derivatives under solvent‐free and catalyst‐free conditions by the reaction of aromatic aldehydes, isatoic anhydride, and ammonium acetate was reported. The advantages of this protocol include sh
## Abstract magnified image A solvent‐ and catalyst‐free one‐pot three‐component condensation reaction approach was developed for the synthesis of a new class of 3‐(2′‐benzothiazolyl)‐2,3‐dihydroquinazolin‐4(1__H__)‐ones in relatively good yields.
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