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Tandem radical addition reactions to substituted indoles under atom-transfer and oxidative conditions

✍ Scribed by Jeffrey H. Byers; Jonathan A. Kosterlitz; Peter L. Steinberg


Book ID
104429931
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
120 KB
Volume
4
Category
Article
ISSN
1387-1609

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✍ Yvan Guindon; RΓ©al C. Denis πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 320 KB

The efficiency of a tandem process featuring an oxy radical cyclization and hydrogen transfer reaction of the resultant carbon-based radical has been demonstrated. This methodology affords 2,3-trans-disubstituted tetrahydrofurans by creating two new contiguous stereogenic centers with high levels of