Tandem Double-Michael-Addition/Cyclizati
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Jing Tan; Xianxiu Xu; Lingjuan Zhang; Yifei Li; Qun Liu
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Article
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2009
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John Wiley and Sons
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English
⚖ 611 KB
## Abstract **Up to four adjacent stereocenters** can be formed stereoselectively in the construction of a pyrrolizidine unit through a novel organocatalytic reaction that involves treatment of various dienones with ethyl isocyanoacetate (see scheme; DBU=1,8‐diazabicyclo[5.4.0]undec‐7‐ene). Mechani