Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles
✍ Scribed by Hodgkinson, Roy C. ;Schulz, Jurgen ;Willis, Michael C.
- Book ID
- 118265821
- Publisher
- Royal Society of Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 123 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1477-0520
- DOI
- 10.1039/b817254d
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📜 SIMILAR VOLUMES
A simple and efficient synthetic route to both isoindolo[2,1-a]indole and its structural isomer indolo[1,2a]indole skeletons is presented. The key steps of the strategy are based on copper-catalysed C aryl -C and C aryl -N bond formation reactions, respectively. Moreover, we report the first copper-
## Abstract The easily installed and removed __N__‐(2‐pyridyl)sulfonyl group exerts complete C2 regiocontrol over the Pd^II^‐catalysed CH alkenylation of indoles and pyrroles, affording the corresponding products in good isolated yields (typically ≥70 %). A remarkable feature of this catalyst syst