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Tandem BRAF Mutations in Primary Invasive Melanomas

✍ Scribed by Thomas, Nancy E.; Alexander, Audrey; Edmiston, Sharon N.; Parrish, Eloise; Millikan, Robert C.; Berwick, Marianne; Groben, Pamela; Ollila, David W.; Mattingly, Dianne; Conway, Kathleen


Book ID
110733163
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
498 KB
Volume
122
Category
Article
ISSN
0022-202X

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## Abstract ## BACKGROUND Desmoplastic melanoma is an uncommon variant of cutaneous melanoma that mimics soft tissue sarcoma both clinically and morphologically. An activating point mutation of the __BRAF__ oncogene has been identified in a high proportion of conventional cutaneous melanomas, but