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Tandem Blaise–Nenitzescu reaction: one-pot synthesis of 5-hydroxy-α-(aminomethylene)benzofuran-2(3H)-ones from nitriles

✍ Scribed by Chun, Yu Sung; Ryu, Ka Yeon; Kim, Ju Hyun; Shin, Hyunik; Lee, Sang-gi

Book ID
111859402
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
142 KB
Volume
9
Category
Article
ISSN
1477-0520

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One-Pot Synthesis of 4-(Alkylamino)-1-(arylsulfonyl)-3-benzoyl-1,5- dihydro-5-hydroxy-5-phenyl-2H-pyrrol-2-ones via a Multicomponent Reaction
✍ Abdolali Alizadeh; Atieh Rezvanian; Long-Guan Zhu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 247 KB

## Abstract An effective route to novel 4‐(alkylamino)‐1‐(arylsulfonyl)‐3‐benzoyl‐1,5‐dihydro‐5‐hydroxy‐5‐phenyl‐2__H__‐pyrrol‐2‐ones **10** is described (__Scheme 2__). This involves the reaction of an enamine, derived from the addition of a primary amine **5** to 1,4‐diphenylbut‐2‐yne‐1,4‐dione,