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Tandem arylation-reduction of acyl heterocycles. Convenient synthesis of benzyl heterocycles

โœ Scribed by Stan S. Hall; Sami E. Farahat

Book ID
112128672
Publisher
Journal of Heterocyclic Chemistry
Year
1987
Tongue
English
Weight
826 KB
Volume
24
Category
Article
ISSN
0022-152X

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Novel synthesis of heterocyclic aryl ami
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โœ Ruben A Tommasi; William M Macchia; David T Parker ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 182 KB

We have developed a novel amidine synthesis that allows the preparation of heterocyclic amidines that were previously unknown and difficult to prepare by published methods. The route involves the lithiation of heterocycles by the action of n-BuLl followed by reaction with carbon disulfide and trappi