Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia

Conditional gene deletion in primary noc

Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia

✍ Nitin Agarwal; Stefan Offermanns; Rohini Kuner 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 659 KB

## Abstract The use of Cre‐loxP technology for conditional mutagenesis in pain pathways had been restricted by the unavailability of mice expressing Cre recombinase selectively in functionally distinct components of the nociceptive system. Here we describe the generation of transgenic mouse lines w