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Tamoxifen induces regression of estradiol-induced mammary cancer in the ACI.COP-Ept2 rat model

โœ Scribed by Rachel L. Ruhlen; Dana M. Willbrand; Cynthia L. Besch-Williford; Lixin Ma; James D. Shull; Edward R. Sauter


Publisher
Springer US
Year
2008
Tongue
English
Weight
643 KB
Volume
117
Category
Article
ISSN
0167-6806

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The chemopreventive efficacy of N-acetyl-L-cysteine (NAC), anethole trithione, miconazole and phenethylisothiocyanate (PEITC), each of which would be expected to alter carcinogen metabolism, was examined in the dimethylbenzanthracene (DMBA) mammary carcinogenesis model. In this protocol, animals wer