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Tamoxifen attenuates inflammatory-mediated damage and improves functional outcome after spinal cord injury in rats

✍ Scribed by Dai-Shi Tian; Jun-Li Liu; Min-Jie Xie; Yan Zhan; Wen-Sheng Qu; Zhi-Yuan Yu; Zhou-Ping Tang; Deng-Ji Pan; Wei Wang

Book ID
111181500
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
561 KB
Volume
109
Category
Article
ISSN
0022-3042

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FK506 reduces tissue damage and prevents
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✍ RubΓ¨n LΓ³pez-Vales; Guillermo GarcΓ­a-AlΓ­as; Joaquim ForΓ©s; Esther Udina; Bruce G. πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 523 KB

## Abstract We examined the efficacy of FK506 in reducing tissue damage after spinal cord injury in comparison to methylprednisolone (MP) treatment. Rats were subjected to a photochemical injury (T8) and were given a bolus of MP (30 mg/kg), FK506 (2 mg/kg), or saline. An additional group received a